What Is
PDRN?
The Short Answer.
PDRN — Polydeoxyribonucleotide — is a DNA fragment derived from nucleotides that signals skin cells to repair, renew, and regenerate. Think of it as handing your skin a set of biological instructions: repair, rebuild, renew.
Originally developed for clinical aesthetic medicine — administered via injections — PDRN has been adapted for topical skincare through advances in low molecular weight formulation. The result is all the cellular renewal power of a clinical treatment delivered through your daily serum.
Skinova's PDRN contained in the product is a mixture of deoxyribonucleotides derived from a controlled purification process of Salmon Trout or Chum Salmon sperm DNA. Guaranteed that the substances contained in the manufacturing of the products are in compliance with the European Cosmetic Regulation (EC) 1223/2009 and its further amendments.
What PDRN Does for Your Skin.
Four clinically grounded benefits that make PDRN the most complete renewal ingredient in modern skincare.
Skin Cell Renewal
PDRN activates the skin's natural regeneration cycle at a cellular level. By stimulating fibroblast proliferation and triggering biological repair pathways, it drives the turnover of damaged cells and the production of fresh, healthy ones — resulting in visibly smoother texture and a genuinely renewed complexion.
Boosts Collagen & HA
PDRN stimulates the skin to produce its own collagen and hyaluronic acid — not by applying these ingredients on top, but by triggering the biological mechanisms that synthesise them internally. Clinical data shows a 25–35% increase in collagen synthesis over 8–12 weeks and a 45% improvement in hydration after just 4 weeks.
Instant Glass Skin Glow
Results begin from the very first use. The emollient-rich formula delivers an immediate glass-skin effect — skin looks luminous, bouncy, and lit-from-within. This dual action of instant cosmetic glow combined with longer-term cellular renewal is what makes PDRN an exceptional addition to any regimen.
Calming & Antioxidant Defense
PDRN acts as a powerful cellular anti-inflammatory and antioxidant by selectively binding to specific skin receptors. This systematically cools active inflammation, suppresses destructive free radicals, and rapidly reduces redness. Because it is completely purified of all allergenic proteins, it is universally safe for all skin types, including hyper-sensitive or post-procedure skin, offering rapid barrier recovery and essential protection against oxidative aging.